The question of whether a tattoo can be done while on certain medications or conditions is a common concern among cancer survivors. Most advice online advises against getting tattoos while taking antibiotics, as they are known to reject pigments. However, some people have found mixed information online, with some doctors confirming it is okay for them to get a tattoo while on antibiotics.
Herceptin, a medication used to treat early lymph node-positive and more advanced/metastatic breast cancers that make too much HER2, can also affect the tattooing process. Some medications can impact the tattooing process, such as blood thinners that may lead to excessive bleeding and immune response modifiers that could affect healing times. Contraception should be used while receiving HERCEPTIN and for 7 months after the last dose of HERCEPTIN.
Tattoos can pose risks to breast cancer survivors, but they can also be a way to mark the end of treatment. Some cancer survivors may want to get a permanent tattoo, such as a nipple tattoo, but it depends on the infection risk and whether they are still in cancer treatment. Epibrow treatment for eyebrows can also be done while on Herceptin.
In conclusion, tattoos are generally safe for cancer survivors as long as they are done by reputable artists and women should consult their doctors before getting a tattoo. It is important to consider the potential health risks associated with tattoos and to consult with a healthcare professional before making any decisions about tattooing.
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tattoo on herceptin | I dont have any tattos, dont like needles or pain. Anyway he wanted me to find out if you can get a tatto while taking herceptin. I thought the … | her2support.org |
Do Tattoos Matter? | Can you share a little about when you were informed that you would need radiation tattoos and what your reaction was? I was thrilled that … | saferradiationtherapy.com |
Tattoos? : r/breastcancer | Do any of you ladies (or gents, not discriminating) have tattoos that commemorate your cancer journey/battle? I just finished up my last … | reddit.com |
📹 Trastuzumab (Herceptin) and Pertuzumab (Perjeta) for Breast Cancer: What You Need to Know
Explore the key differences between Trastuzumab (Herceptin) and Pertuzumab (Perjeta), two critical treatments for HER2-positive …
Are You Immunocompromised While On Herceptin?
Trastuzumab (Herceptin) can impact the immune system, potentially increasing the risk of contracting coronavirus and experiencing severe illness, particularly when combined with chemotherapy. While trastuzumab is an effective treatment for HER2-positive breast and gastric cancers both before and after surgery, patients undergoing this treatment should be mindful of their heightened vulnerability to infections like COVID-19. Full vaccination against COVID-19 is recommended as it can help mitigate these risks.
Trastuzumab works by inhibiting HER2 receptors, which are responsible for signaling cells to grow and divide, thus potentially stopping cancer progression. It also has immune-modulating effects, signaling the immune system to target and destroy cancer cells. Though it is associated with side effects, trastuzumab is generally less likely to cause severe side effects compared to chemotherapy.
Cancer treatment often leads to immunocompromise, which is why individuals with breast cancer are classified as high-risk. Hence, healthcare professionals and patients must consider the implications of trastuzumab in the context of infectious diseases. It’s essential for patients who have undergone treatments such as chemotherapy, surgery, and trastuzumab therapy to remain vigilant about their health and take necessary precautions against infections. Researchers continue to explore the complex relationship between the immune system and HER2-positive breast cancer to optimize treatment outcomes and patient safety.
Does Herceptin Work On HER2?
Herceptin (trastuzumab) is a targeted therapy for HER2-positive breast cancer, which involves an overexpression of the HER2 protein. This protein, known as human epidermal growth factor receptor 2, signals cells to grow and divide. When cancer tests indicate that it cannot be surgically removed, Herceptin and other treatments may shrink the cancer enough to allow for surgery. Additionally, if the cancer has metastasized to other body parts, Herceptin can help slow its progression.
Herceptin is effective for both early and advanced breast cancers that exhibit high levels of HER2. It works by binding to HER2 receptors on cancer cells, inhibiting signals that promote cell growth and division, and potentially triggering the immune system to act against the cancer. Research has established that the use of Herceptin before and after surgery can improve patient outcomes.
The mechanism of action for Herceptin involves attaching to the HER2 protein, preventing it from transmitting growth signals and thereby inhibiting tumor growth. Specifically, Herceptin binds to the receptor's extracellular regions, shutting down the signaling pathways that lead to cancer cell proliferation.
Studies show that when Herceptin is combined with chemotherapy, it can significantly reduce the risk of cancer recurrence and lower mortality rates by up to one-third for early-stage HER2-positive breast cancer. The treatment is approved for patients with metastatic disease who have undergone one or more courses of chemotherapy. Despite its effectiveness, some HER2-positive breast cancers may not respond adequately to Herceptin, necessitating the exploration of alternative treatments.
Recent findings suggest that Herceptin binds specifically to the juxtamembrane domain of HER2, resulting in decreased HER2 expression and disrupted signaling pathways involved in cell proliferation. In addition to Herceptin, other therapies, such as neratinib, have been indicated for patients who have completed trastuzumab treatment and still exhibit HER2-positive tumors.
Overall, Herceptin represents a critical advancement in personalized medicine for HER2-positive breast cancer, providing both pre- and post-surgical treatment options aimed at combating advanced stages of the disease.
Can I Get Pregnant While Taking Herceptin?
Contraception is essential while undergoing HERCEPTIN treatment and for 7 months following the final dose. Pregnant women or those who become pregnant during this period must report their HERCEPTIN exposure to Genentech at 1-888-835-2555. HERCEPTIN is contraindicated during pregnancy as it may cause severe harm or even death to an unborn child. Effective birth control methods should be utilized to prevent pregnancy during treatment and for 7 months thereafter. If pregnancy occurs while receiving HERCEPTIN HYLECTA or within 7 months of the last dose, it is also recommended to report the exposure.
HERCEPTIN has significantly improved the management of advanced HER2-positive breast cancer. Therefore, individuals capable of becoming pregnant should diligently use contraception while on this medication and for at least 7 months post-treatment due to its potential adverse effects on fetal development. Notably, HERCEPTIN may reduce the amount of amniotic fluid which can lead to fetal harm or death if pregnancy occurs during therapy or shortly after its completion.
HERCEPTIN’s half-life is about 12 days, suggesting that it takes roughly 60 days for minimal traces to remain in the body. However, consultation with a healthcare professional is prudent before discontinuing contraception. Health authorities recommend adherence to these guidelines to ensure informed decisions regarding medication use during pregnancy.
While the targeted therapy trastuzumab (HERCEPTIN) is typically given over a year and generally does not affect fertility, caution is advised. The risk of unintended pregnancy while on treatment should not be underestimated, given potential threats to fetal health. Instances of spontaneous abortion have been observed, highlighting the importance of avoiding conception during both treatment and the subsequent months.
In conclusion, for patients undergoing HERCEPTIN therapy, prioritizing contraception is vital to prevent potential dangers to an unborn child, with recommendations advocating for a delay in pregnancy for several months following treatment completion to ensure safety for future pregnancies.
Is It Safe To Get A Tattoo After Breast Cancer?
The best time to get a tattoo after breast cancer surgery is when scars are fully healed and all chemotherapy or radiation treatments are complete, which can take months to over a year. Many clients who have undergone breast cancer treatment have chosen tattoos to cover mastectomy scars or to get nipple tattoos after breast reconstruction. However, health complications can arise for breast cancer survivors, especially as they may still be recovering.
A mastectomy tattoo is a decorative tattoo that individuals may consider; but the risk of lymphedema, a condition characterized by fluid buildup due to lymph node removal, persists indefinitely. Tattoos are perceived by the body as trauma, which can exacerbate symptoms of lymphedema, particularly after a skin injury. Therefore, waiting at least a year post-surgery is advisable to allow adequate healing and to minimize interference with surgical sites.
Potential tattoo recipients should consult with their treatment teams and ensure complete recovery from cancer treatments before making a decision. For those who have undergone lymph node removal, such as in my case, it is particularly emphasized to avoid tattoos on the affected side due to increased infection risk.
In summary, essential factors to consider before getting a tattoo include ensuring that scars are completely healed (ideally waiting longer than a year), finishing all treatments, and consulting with healthcare professionals. Breast Cancer Care offers more resources on artistic tattoos following breast surgery, and individuals should prioritize their health and well-being in this decision-making process. After fully healing from surgery, including reconstruction, it is generally safe to consider tattoos, including designs over breast implants.
Should I Take Medication Before Getting A Tattoo?
Taking medications such as aspirin prior to getting a tattoo is not advisable, as it can significantly hinder the body's ability to clot, particularly during the initial healing phase. Pain relievers like ibuprofen can disrupt the tattooing process and should also be avoided. Prior to your tattoo appointment, it’s essential to refrain from any blood-thinning medications, as well as substances that may heighten skin sensitivity or provoke rejection reactions.
Consulting with your tattoo artist ahead of time is also recommended to discuss any anxieties and obtain their professional advice on pain management strategies. While some individuals opt for acetaminophen (Tylenol) an hour before the procedure to mitigate pain, it’s crucial to avoid anticoagulant medications such as warfarin or heparin. These types of prescriptions dramatically thin the blood and can lead to excessive bleeding during the tattooing process; thus, a consultation with a healthcare provider is vital if you are on such medications.
The general consensus is to steer clear of over-the-counter pain medications before tattooing due to their potential to complicate matters. Specifically, you should refrain from taking aspirin or ibuprofen for at least 24 hours prior to your session to minimize bleeding. Alcohol should also be avoided in this timeframe for the same reason.
Although antibiotics may be indicated for certain health conditions, they are not routinely required before tattooing. It is important to consider that each individual’s body reacts differently to medications, making personal health history critical in this context.
For tattoo removal procedures, anecdotal evidence suggests that it may be safe to take Tylenol to manage pain; however, consulting a healthcare provider is essential. During the tattooing process, artists usually do not administer pain relief, and the potential risks associated with blood-thinning medications—similar to those related to alcohol consumption—should not be underestimated. Patients should always inform their tattoo artist about any medications they are taking to avoid complications. To summarize, ensure open communication about medications with both your healthcare provider and tattoo artist to guarantee a safe and smooth tattooing experience.
Can Immunosuppressed Patients Get Tattoos?
Immunosuppressed individuals face heightened infection risks, including from cutaneous mycobacterial infections, making them more susceptible to complications from tattoos. Many of these patients are young adults interested in tattoos, yet their immunosuppressed status needs careful consideration. Doctors indicate that tattooing can introduce infections from various organisms like Clostridium tetani and Staphylococcus aureus, as outlined in BMJ Case Reports.
This report highlights a case of inflammatory myopathy in an immunosuppressed patient following tattooing. Immunosuppressive medications make patients vulnerable to infections due to a weakened immune system, increasing the likelihood of complications. It is crucial to inform such patients about the possibility of developing lesions or infections on tattoos, considering their compromised immune response disrupts the skin’s barriers and alters the cutaneous ecosystem.
Although there is no definitive evidence linking tattoos to serious complications in lupus patients, the condition does affect skin healing. Hence, the need for cautious consideration regarding tattoos for immunocompromised individuals is evident. Many with autoimmune diseases get tattoos without lasting effects, yet consulting healthcare professionals for personalized advice is essential. Current guidelines suggest that individuals with active psoriasis and on immunosuppressive treatment should avoid tattoos. Ultimately, doctors must proactively counsel immunosuppressed patients about the risks associated with tattooing to ensure informed decision-making.
Are There Any Serious Side Effects With Herceptin Therapy?
HERCEPTIN therapy is associated with common side effects, though not everyone experiences serious complications. While life-threatening side effects can occur, most patients do not face such risks. It's crucial for individuals to contact their doctor if they notice any serious symptoms, as treatment will be halted if adverse effects arise. Serious and potentially fatal infusion reactions and pulmonary toxicity can manifest during or within 24 hours post-administration. Signs of distress may include symptoms consistent with infection—such as fever, chills, or general malaise—requiring immediate medical consultation.
The serious side effects associated with HERCEPTIN, particularly in breast cancer treatment, include heart issues and pulmonary complications. Potential severe reactions can encompass dyspnea, interstitial pneumonitis, pulmonary infiltrates, and other forms of pulmonary dysfunction. It’s important to seek emergency help if symptoms escalate to life-threatening conditions or if significant chest pain occurs.
Patients undergoing HERCEPTIN therapy should be vigilant about the possibility of fluid accumulation around the heart (pericardial effusion) and lung-related issues, even though such occurrences are rare. Mild to moderate side effects, including nausea, bone pain, and allergic reactions, have also been reported. Infusion reactions and changes in breathing dynamics can develop, warranting immediate medical assistance.
HERCEPTIN HYLECTA tends to have side effects similar to those of HERCEPTIN, with tiredness, joint pain, diarrhea, and injection site reactions being the most frequently observed. Healthcare providers will monitor patients for adverse reactions, and individuals experiencing troubling symptoms throughout their treatment should not hesitate to reach out to their medical professional.
In summary, while many may undergo HERCEPTIN therapy without severe effects, awareness and prompt communication with a healthcare provider upon experiencing any discomfort or warning signs are essential for ensuring patient safety during treatment.
Can I Take Herceptin For A Second Year?
Recent studies indicate that extending Herceptin treatment for a second year may not be beneficial. Instead, shorter regimens of six months or less could be effective in preventing recurrence of early HER2-positive breast cancers. Treatment length for Herceptin varies by hospital, but it is typically recommended for one year, equating to up to 18 cycles. When combined with chemotherapy, Herceptin is administered weekly, while post-surgery, it might be given after chemotherapy has been completed.
In the U. S., trials have primarily focused on a full year of Herceptin for patients with curable breast cancer and showed it benefits overall survival after a median follow-up. Some patients have experienced side effects impacting their heart function, leading to temporary breaks in treatment, but oncologists often find ways to accommodate continued therapy.
Many patients report prolonged stability while on Herceptin. For instance, one patient remained stable for nine years post-diagnosis in 2006, and another continued Herceptin indefinitely after a favorable response. A typical protocol may combine Taxol with Herceptin for a set duration, transitioning to Herceptin alone for an additional period, resulting in an overall treatment span of approximately 15 months.
Meta-analyses from trials such as the HERA study suggest that one year of Herceptin is more effective than two years or six months in reducing recurrence rates for women diagnosed with HER2-positive breast cancer. The standard practice is predominantly one year unless adverse effects arise that necessitate earlier termination. Herceptin is administered as an intravenous infusion, and while it may not improve symptoms, it is critical in managing tumor size.
Furthermore, the consistency of these findings underscores one year as the recommended length of treatment for patients with HER2-positive breast cancer, with ongoing studies further corroborating this approach.
What To Avoid While On Herceptin?
During Herceptin treatment, it is essential to limit or avoid specific foods and beverages to optimize the effectiveness of the medication and ensure patient safety. Key items to avoid include alcohol, beef, high-copper foods (such as most nuts, liver, and shellfish), grapefruit and its juice, lime juice and peel, pomelos, sugar, and high-fructose corn syrup. These foods may reduce Herceptin's effectiveness, promote growth in HER2+ breast cancer cells, or increase HER2+ expression.
Patients should also adhere to their doctor's guidance regarding dietary restrictions and lifestyle changes while receiving Herceptin, which treats certain breast and stomach cancers by interfering with cancer cell growth. It is crucial to get immediate medical assistance if signs of an allergic reaction to Herceptin occur, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.
To manage side effects like nausea, patients are advised to consume smaller, more frequent meals, favoring lighter and less spicy options over rich foods. It's also recommended to avoid caffeine, heavy meals, and exercise before bedtime to promote better rest. Additionally, Herceptin should not be mixed with dextrose in water or combined with other medications; proper mixing with sterile water for injection is necessary.
Those taking Herceptin should be mindful of potential side effects, including heart issues and interstitial lung disease, especially when combined with other cancer treatments. It is advised to avoid contact with individuals with infections and report any unusual bleeding or bruising to a healthcare provider promptly.
For women of childbearing age, contraception is recommended during treatment and for seven months afterward due to the risk of birth defects or potential harm to an unborn baby. Breastfeeding is also discouraged during therapy. Overall, following dietary and lifestyle modifications can support the treatment journey while managing HER2+ breast cancer effectively.
📹 Herceptin (trastuzumab) for HER2-Positive Breast and Stomach Cancer
Herceptin (trastuzumab) is an approved #targetedtherapy cancer treatment for breast, stomach and esophagus cancers that are …
I have been in remission/maintenance for 3 years. I get pertuzumab/trastuzamab in my leg every 21 days. I have never had surgery. It is no longer in my breast, but remains in my bone and is monitored every 4 months. My side effects are mild and only a little neuropathy remains in my feet and mostly acts up at night. My cancer marker blood test is very low in the normal range.
Thank you. This was helpful. I had to look up the other names for these medicines since my doctor called them Herceptin and Perjeta. I had them both at the same time before surgery. At first they game me a combo of them both together in a shot, but it was extremely painful for me. It was a 6 minute “push” which I had never heard of before. It was extremely painful and later I opted for an IV drip which made the infusion longer, but less painful. Please consider discussing Kadcyla. I was on that for 14 rounds. I had a difficult time tolerating it. Thanks!
Thank you Dr Griggs, this information is perfect, I’ve tried to do some research myself for my mothers ER+, PR-, HER2+ cancer and everything Dr Griggs said in this article about the 2 drugs tracks with what our medical oncologist shared with us. She is currently on 3 cycles of Docetaxel, Trastuzumab + Pertuzumab, followed by 3 cycles of fluorouracil, epirubicin and cyclophosphamide (FEC). This is neoadjuvant chemo before surgery, I hope it goes well… The fatigue is real on the 3rd/4th day after chemo but it definitely gets better! Stay strong everyone